Die wirksamen Bestandtheile von Buxus sempervirens

Buxus alkaloids. XIV.* Alkaloids from Buxus sempervirens var. angustifolia WEST

Various species of common box (Buxus) are cultivated in the Arboretum of the Slovak Academy of Sciences in Mlyňany under the same soil and climatic conditions; consequently, the examination of alkaloids produced by those plants is of chemotaxonomical importance. From this locality we investigated so far alkaloids from Buxus sempervirens L.[l,2], B. microphylla SIEB, et ZUCC. var. sinica REHD. e...

New triterpenoidal alkaloids from Buxus sempervirens.

Phytochemical studies on the ethanolic extract of the roots of Buxus sempervirens of Turkish origin have resulted in the isolation of two new triterpenoidal alkaloids, (+)-16a, 31-diacetylbuxadine (1), (-)-Nb-demethylcyclomikuranine (2) along with three known natural products, (-)-cyclomikuranine (3), (-)-cyclobuxophylline-K (4) and (+)-buxaquamarine (5) isolated for the first time from this sp...

Acetonic Extract of Buxus sempervirens Induces Cell Cycle Arrest, Apoptosis and Autophagy in Breast Cancer Cells

Plants are an invaluable source of potential new anti-cancer drugs. Here, we investigated the cytotoxic activity of the acetonic extract of Buxus sempervirens on five breast cancer cell lines, MCF7, MCF10CA1a and T47D, three aggressive triple positive breast cancer cell lines, and BT-20 and MDA-MB-435, which are triple negative breast cancer cell lines. As a control, MCF10A, a spontaneously imm...

Die Leitwarte von heute verstehen - die Leitwarte von morgen gestalten!

In diesem Beitrag wird eine domänenübergreifende Nutzungskontextanalyse vorgestellt, vor dem Hintergrund der Herausforderung einer stetig ansteigenden Komplexität der Mensch-MaschineSchnittstelle in der Arbeitsumgebung von Leitwartenoperatoren. Die mittels teilnehmender Beobachtung und teilstrukturierten Interviews durchgeführte Erhebung in Leitwarten hatte die Zielsetzung Gemeinsamkeiten in Be...

Die Bedeutung von nationaler Kultur für die Gestaltung von Informationssystemen